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CharlesDexterWard'swifeenliststhehelpofaprivatedetectivetofindoutwhatherhusbandisuptoinaremotecabinownedbyhisfamilyforcenturies.Thaaa husbandisachemicalengineer|andthesmellsfromhisexperiments(andthedeliveryofwhatappeartobehumanremainsatallhours)arebeginningtoarousethe attentionofneighborsandlocallawenforcementofficials.Whenthedetectiveandwifefindadiaryofthehusband'sancestorfrom1771|andreportsofgruesome murdersintheareabegintosurface|theybegintosuspectthatsomeveryunnaturalexperimentsarebeingconductedintheoldhouse.BasedonanH.P.Lovecraft